Synthetic peptide: EDGVYEPPDLTP, from the N-terminus of human Cytohesin 2
Conjugate
Unconjugated
Applications
Application Notes
WB: Use at a concentration of 0.5 - 1.5 μg/ml. Detects a band of approximately 48 kDa (predicted molecular weight: 46 kDa). Peptide ELISA: antibody detection limit dilution 1:32,000.
Target
Alternative Names
CYTH2; cytohesin 2; ARNO; CTS18; PSCD2; SEC7L; PSCD2L; CTS18.1; Sec7p-L; Sec7p-like; cytohesin-2; CTC-273B12.8; ARF exchange factor; ARF nucleotide-binding site opener; PH, SEC7 and coiled-coil domain-containing protein 2; pleckstrin homology, Sec7 and co
Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane.
Pathway
Arf1 pathway; Class I PI3K signaling events;
Citations
Publication ()
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COA
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