Anti-CYP7B1 (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Full length protein corresponding to Human CYP7B1 aa 1-506. (NCBI: NP_004811.1)Sequence: MAGEVSAATGRFSLERLGLPGLALAAALLLLALCLLVRRTRRPGEPPLIK GWLPYLGVVLNLRKDPLRFMKTLQKQHGDTFTVLLGGKYITFILDPFQYQ LVIKNHKQLSFRVFSNKLLEKAFSISQLQKNHDMNDELHLCYQFLQGKSL DILLESMMQNLKQ

Conjugate

Application Notes

WB: 1 μg/ml.

Alternative Names

CYP7B1; cytochrome P450, family 7, subfamily B, polypeptide 1; cytochrome P450, subfamily VIIB (oxysterol 7 alpha hydroxylase), polypeptide 1; spastic paraplegia 5A (autosomal recessive); SPG5A; 25-hydroxycholesterol 7-alpha-hydroxylase; cytochrome P450 7

Entrez Gene ID

UniProt ID

Antigen Description

CYP7B1 (cytochrome P450, family 7, subfamily B, polypeptide 1) is a protein-coding gene. Diseases associated with CYP7B1 include bile acid synthesis defect, congenital, 3, and spastic paraplegia 5a, and among its related super-pathways are Synthesis of bile acids and bile salts and Cytochrome P450 - arranged by substrate type. GO annotations related to this gene include electron carrier activity and heme binding. An important paralog of this gene is CYP39A1.

Pathway

Bile acid and bile salt metabolism; Biological oxidations; Cytochrome P450 - arranged by substrate type; Endogenous sterols; Metabolism; Metabolism of lipids and lipoproteins; Phase 1 - Functionalization of compounds