Anti-CYP51A1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human CYP51A1 is used for rabbit immunization.

Conjugate

Alternative Names

CYP51A1; cytochrome P450, family 51, subfamily A, polypeptide 1; LDM; CP51; CYP51; CYPL1; P450L1; P450-14DM; lanosterol 14-alpha demethylase; CYPLI; cytochrome P450LI; cytochrome P45014DM; cytochrome P450 51A1; cytochrome P450-14DM; sterol 14-alpha demeth

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Pathway

Activation of Gene Expression by SREBP (SREBF); Biological oxidations; Cholesterol biosynthesis; Cholesterol biosynthesis; Cholesterol biosynthesis, squalene 2,3-epoxide cholesterol; Cholesterol biosynthesis, squalene 2,3-epoxide cholesterol; Cytochrome P450 - arranged by substrate type; Endogenous sterols; Metabolism; Metabolism of lipids and lipoproteins; Phase 1 - Functionalization of compounds;