Specifications
Immunogen
Synthetic peptide conjugated to KLH, corresponding to a sequence within internal amino acids 339-369 of Human CYP4B1.
Applications
Application Notes
WB: 1/50 - 1/100; IHC-P: 1/50 - 1/100; ICC/IF: 1/10 - 1/50.
Target
Alternative Names
CYP4B1; cytochrome P450, family 4, subfamily B, polypeptide 1; cytochrome P450, subfamily IVB, polypeptide 1; cytochrome P450 4B1; cytochrome P450-HP; microsomal monooxygenase; CYPIVB1; P-450HP;
Product Background
Antigen Description
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Pathway
Biological oxidations; Cytochrome P45 - arranged by substrate type; Fatty acids; Metabolism; Nuclear receptors in lipid metabolism and toxicity; Phase 1 - Functionalization of compounds.
Citations
Publication ()
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COA
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