Anti-CYP2F1 (aa 191-290) polyclonal antibody

Species Reactivity

Human

Immunogen

CYP2F1 (NP_000765, 191 a.a. ~ 290 a.a) partial recombinant protein with GST tag. The sequence is DDERLLTIIRLINDNFQIMSSPWGELYDIFPSLLDWVPGPHQRIFQNFKCLRDLIAHSVH DHQASLDPRSPRDFIQCFLTKMAEEKEDPLSHFHMDTLLM

Conjugate

Alternative Names

CYP2F1; cytochrome P450, family 2, subfamily F, polypeptide 1; C2F1; CYP2F; cytochrome P450 2F1; CYPIIF1; microsomal monooxygenase; xenobiotic monooxygenase; flavoprotein-linked monooxygenase; cytochrome P450, subfamily IIF, polypeptide 1;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q.

Pathway

Biological oxidations; Cytochrome P45 - arranged by substrate type; Metabolism; Metabolism of xenobiotics by cytochrome P45.