Specifications
Immunogen
Synthetic peptide within Human CYP2C18 aa 456-485 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: P33260
Applications
Application Notes
WB: 1/1000; IHC-P: 1/50 - 1/100.
Target
Alternative Names
CYP2C18; cytochrome P450, family 2, subfamily C, polypeptide 18; CYP2C17, cytochrome P450, subfamily IIC (mephenytoin 4 hydroxylase), polypeptide 18; cytochrome P450 2C18; CPCI; CYP2C; P450IIC17; CYPIIC18; cytochrome P450-6B/29C; microsomal monooxygenase;
Product Background
Antigen Description
CYP2C18 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP2C18 oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
Pathway
Arachidonic acid metabolism; Biological oxidations; Cytochrome P450 - arranged by substrate type; Drug metabolism - cytochrome P450; FOXA1 transcription factor network;
Citations
Publication ()
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COA
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