Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Recombinant fragment, corresponding to C terminal amino acids 194-350 of Human CKII alpha prime polypeptide expressed in E. Coli.
Applications
Application Notes
WB: 1/500 - 1/2000; Flow Cyt: 1/200 - 1/400;
Target
Alternative Names
CSNK2A2; casein kinase 2, alpha prime polypeptide; casein kinase II subunit alpha; CSNK2A1; CK II alpha; CK2A2; FLJ43934;
Product Background
Antigen Description
Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates Ser-392 of p53/TP53 following UV irradiation.
Pathway
Adherens junction, organism-specific biosystem; Adherens junction, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; L1CAM interactions, organism-specific biosystem;
Citations
Publication ()
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COA
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