Anti-CSNK1A1 monoclonal antibody, clone 4D20G8D22

Antibody Isotype

IgG1

Clone

4D20G8D22

Species Reactivity

Human

Immunogen

Recombinant protein corresponding to human CSNK1A1.

Conjugate

Application Notes

ELISA (1:10000); WB (1:500-1:2000); Immunohistochemistry (1:200-1:1000) & The optimal working dilution should be determined by the end user.

Alternative Names

CSNK1A1; casein kinase 1, alpha 1; casein kinase I isoform alpha; CK1; CK1a; CK1alpha; CKIa; CKIalpha; clock regulator kinase; CKI-alpha; down-regulated in lung cancer; HLCDGP1; PRO2975;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes proteins related to the first discovered blood group system, ABO. Which allele is present in an individual determines the blood group. The O blood group is caused by a deletion of guanine-258 near the N-terminus of the protein which results in a frameshift and translation of an almost entirely different protein. Individuals with the A, B, and AB alleles express glycosyltransferase activities that convert the H antigen into the A or B antigen. Other minor alleles have been found for this gene.

Pathway

Beta-catenin phosphorylation cascade, organism-specific biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Degradation of beta-catenin by the destruction complex, organism-specific biosystem; FoxO family signaling, organism-specific.