Anti-CROT (aa 2-99) polyclonal antibody

Species Reactivity

Human

Immunogen

CROT (NP_066974, 2 a.a. ~ 99 a.a) partial recombinant protein with GST tag. The sequence is ENQLAKSTEERTFQYQDSLPSLPVPSLEESLKKYLESVKPFANQEEYKKTEEIVQKFQSG IGEKLHQKLLERAKGKRNWLEEWWLNVAYLDVRIPSQL

Conjugate

Alternative Names

CROT; carnitine O-octanoyltransferase; COT; peroxisomal carnitine O-octanoyltransferase; peroxisomal carnitine acyltransferase;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]

Pathway

Beta-oxidation of pristanoyl-CoA; Metabolism of lipids and lipoproteins; Peroxisome;