The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Overexpression of this gene has been shown to induce apoptosis in cells. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported for this gene. [provided by RefSeq, May 2009]
Pathway
Direct p53 effectors
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More
Citations
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Fan, JQ; Ponferrada, VG; et al. Crim1 maintains retinal vascular stability during development by regulating endothelial cell Vegfa autocrine signaling. DEVELOPMENT 141:448-459(2014).
Uhlen, M; Bjorling, E; et al. A human protein atlas for normal and cancer tissues based on antibody proteomics. MOLECULAR & CELLULAR PROTEOMICS 4:1920-1932(2005).
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COA
Certificate of Analysis
