Specifications
Species Reactivity
Mouse; Rat; Cow; Human
Immunogen
Human liver mitochondria
Applications
Application Notes
IHC-P: 10 μg/ml; ICC/IF: 4 μg/ml; Flow Cyt: 1 μg/ml; In-Cell ELISA: 4 μg/ml.
Target
Alternative Names
CPT2; carnitine palmitoyltransferase 2; carnitine palmitoyltransferase II , CPT1; carnitine O-palmitoyltransferase 2, mitochondrial; CPTASE; CPT II; carnitine palmitoyltransferase II; CPT1; IIAE4;
Product Background
Antigen Description
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.
Pathway
Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; Fatty acid metabolism, conserved biosystem; Fatty acid, triacylglycerol, and ketone body metabolism, organism-specific biosystem; Import of palmitoyl-CoA into the mitochondrial matrix, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem;
Citations
Publication ()
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