Anti-CPSF6 monoclonal antibody, clone 2D6

Antibody Isotype

IgG2b

Clone

2D6

Species Reactivity

Human; Mouse

Immunogen

CPSF6 (NP_008938, 37 a.a. ~ 136 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

CPSF6; cleavage and polyadenylation specific factor 6, 68kDa; cleavage and polyadenylation specific factor 6, 68kD subunit; cleavage and polyadenylation specificity factor subunit 6; CFIM; CFIM68; HPBRII 4; HPBRII 7; protein HPBRII-4/7; CPSF 68 kDa subuni

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is one subunit of a cleavage factor required for 3 RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3 end processing complex and facilitates the recruitment of other processing factors. The cleavage factor complex is composed of four polypeptides. This gene encodes the 68kD subunit. It has a domain organization reminiscent of spliceosomal proteins.

Pathway

mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem;