Anti-COX7C monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human COX7C is used for rabbit immunization.

Conjugate

Alternative Names

COX7C; cytochrome c oxidase subunit VIIc; cytochrome c oxidase subunit 7C, mitochondrial; cytochrome-c oxidase chain VIIc; cytochrome c oxidase polypeptide VIIc;

Entrez Gene ID

UniProt ID

Antigen Description

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes subunit VIIc, which shares 87% and 85% amino acid sequence identity with mouse and bovine COX VIIc, respectively, and is found in all tissues. A pseudogene COX7CP1 has been found on chromosome 13.

Pathway

Alzheimers disease; Alzheimers disease; Cardiac muscle contraction; Cardiac muscle contraction; Cytochrome c oxidase; Cytochrome c oxidase; Electron Transport Chain; Huntingtons disease; Huntingtons disease; Metabolism; Non-alcoholic fatty liver disease (NAFLD);