Recombinant human CORO1B protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 393-489 aa of BC006449
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:1000-1:4000 IHC: 1:50-1:500
General Notes
This product (Catalog No. DPABH-13739) is a rabbit-derived polyclonal antibody raised against human CORO1B, targeting the amino acid region 393–489 of the protein. This antibody exhibits cross-reactivity with Human CORO1B from mouse and rat. It has been affinity purified by Protein A. CORO1B (Coronin 1B) is an actin-binding protein that controls actin networks at classical lamellipodia (PMID: 32850828). Coro1B localizes to the plasma membrane, regulates lamellipodia formation, and when phosphorylated, it can no longer bind ARP2/3 and inhibit its actin nucleation abilities (PMID: 22619279). DPABH-13739 is suitable for use in Western blot (WB) (1:1,000–1:4,000), IHC (1:50–1:500) applications. DPABH-13739 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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