CNOT7 (NP_037486, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MKKIRQVIRKYNYVAMDTEFPGVVARPIGEFRSNADYQYQLLRCNVDLLKIIQLGLTFMN EQGEYPPGTSTWQFNFKFNLTEDMYAQDSIELLTTSGIQF
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The protein has both mouse and yeast orthologs. Alternate splicing of this gene results in two transcript variants encoding different isoforms.
Pathway
Deadenylation of mRNA; Gene Expression; RNA degradation.
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