Group I (dsDNA); Herpesviridae; Betaherpesvirinae; Cytomegalovirus; 45 kDa immediate-early protein 2; 55 kDa immediate-early protein 2; HCMV; HHV 5; Human Herpesvirus 5; IE1; IE2; Immediate-early protein 1; Immediate-early protein 2; UL122; UL123
Product Background
Antigen Description
The IE1/2 transcriptional control region of human cytomegalovirus drives the expression of the HCMV major immediate-early genes (UL123-122), which encode proteins necessary for initiation of the virus replicative cycle. Nucleotide sequence polymorphism in this region of the viral genome could account for variations in the replication of human cytomegalovirus strains.
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