Anti-CMTM7 monoclonal antibody (DCABH-11062)

Mouse anti-Human CMTM7 monoclonal antibody for ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
T2
Species Reactivity
Human
Immunogen
CMTM7 (AAH10116.1, 1 a.a. ~ 175 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
CMTM7; CKLF-like MARVEL transmembrane domain containing 7; chemokine like factor super family 7 , chemokine like factor superfamily 7 , CKLFSF7; CKLF-like MARVEL transmembrane domain-containing protein 7; FLJ30992; chemokine-like factor superfamily 7
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CMTM7 (CKLF Like MARVEL Transmembrane Domain Containing 7) is a Protein Coding gene. GO annotations related to this gene include cytokine activity. This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor that regulates G1/S transition in the cell cycle, and epidermal growth factor receptor/protein kinase B signaling during tumor pathogenesis. Alternative splicing results in multiple transcript variants encoding different isoforms.
Antigen Description
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. Protein Symbol:Q96FZ5-CKLF7_HUMANRecommended name:CKLF-like MARVEL transmembrane domain-containing protein 7Protein Accession:Q96FZ5Secondary Accessions:Q5VLK1The function about CMTM7 antigen include cytokine activity.

Citations


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References


Sugimoto, N; Oida, T; et al. Foxp3-dependent and -independent molecules specific for CD25(+)CD4(+) natural regulatory T cells revealed by DNA microarray analysis. INTERNATIONAL IMMUNOLOGY 18:1197-1209(2006).
Zhang, YF; Wang, JY; et al. A role for CMTM7 in BCR expression and survival in B-1a but not B-2 cells. INTERNATIONAL IMMUNOLOGY 26:47-57(2014).

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