Anti-CLCN5 (aa 566-665) polyclonal antibody

Species Reactivity

Human

Immunogen

CLCN5 (NP_000075, 566 a.a. ~ 665 a.a) partial recombinant protein with GST tag. The sequence is GYPFLEAKEEFAHKTLAMDVMKPRRNDPLLTVLTQDSMTVEDVETIISETTYSGFPVVVS RESQRLVGFVLRRDLIISIENARKKQDGVVSTSIIYFTEH

Conjugate

Alternative Names

CLCN5; chloride channel, voltage-sensitive 5; XRN; CLC5; XLRH; CLCK2; ClC-5; DENTS; NPHL1; NPHL2; hCIC-K2; H(+)/Cl(-) exchange transporter 5; chloride transporter ClC-5; voltage-gated chloride ion channel CLCN5;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the ClC family of chloride ion channels and ion transporters. The encoded protein is primarily localized to endosomal membranes and may function to facilitate albumin uptake by the renal proximal tubule. Mutations in this gene have been found in Dent disease and renal tubular disorders complicated by nephrolithiasis. Alternatively spliced transcript variants have been found for this gene.

Pathway

Ion channel transport; Transmembrane transport of small molecules;