CHST4 (NP_005760, 221 a.a. ~ 320 a.a) partial recombinant protein with GST tag. The sequence is LMIDSRIVMGQHEQKLKKEDQPYYVMQVICQSQLEIYKTIQSLPKALQERYLLVRYEDLA RAPVAQTSRMYEFVGLEFLPHLQTWVHNITRGKGMGDHAF
This gene encodes an N-acetylglucosamine 6-O sulfotransferase. The encoded enzyme transfers sulfate from 3phosphoadenosine 5phospho-sulfate to the 6-hydroxyl group of N-acetylglucosamine on glycoproteins. This protein is localized to the Golgi and is involved in the modification of glycan structures on ligands of the lymphocyte homing receptor L-selectin. Alternate splicing in the 5 UTR results in multiple transcript variants that encode the same protein.
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