This gene is a member of the ligand-gated ionic channel family and nicotinic acetylcholine receptor gene superfamily. It encodes a plasma membrane protein that forms homo- or hetero-oligomeric divalent cation channels. This protein is involved in cochlea hair cell development and is also expressed in the outer hair cells (OHCs) of the adult cochlea.
Pathway
Acetylcholine Binding And Downstream Events; Activation of Nicotinic Acetylcholine Receptors; Highly calcium permeable postsynaptic nicotinic acetylcholine receptors; Neuroactive ligand-receptor interaction; Neuroactive ligand-receptor interaction; Neuronal System; Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell; Postsynaptic nicotinic acetylcholine receptors; Transmission across Chemical Synapses;
Citations
Publication ()
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