Recombinant full length protein corresponding to Human p60 CAF1 aa 1-559. Produced in HEK293T cells (NP_005432).Sequence: MKVITCEIAWHNKEPVYSLDFQHGTAGRIHRLASAGVDTNVRIWKVEKGP DGKAIVEFLSNLARHTKAVNVVRFSPTGEILASGGDDAVILLWKVNDNKE PEQIAFQDEDEAQLNKENWTVVKTLRGHLED
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/200 - 1/2000; IHC-P: 1/150; ICC/IF: 1/100;
Target
Alternative Names
CHAF1B; chromatin assembly factor 1, subunit B (p60); chromatin assembly factor 1 subunit B; CAF 1; CAF1; CAF1A; CAF1P60; Chromatin assembly factor I; p60 subunit; human chromatin assembly factor I p60 subunit; M phase phosphoprotein 7; MPHOSPH7; MPP7; CA
Complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. The CCR4-NOT complex functions as general transcription regulation complex.
Citations
Publication ()
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