Specifications
Immunogen
Recombinant fragment, corresponding to amino acids 57-139 of Human LASS4 with proprietary tag (NP_078828).
Applications
Application Notes
WB: 1 - 5 μg/ml; Sandwich ELISA: 10 μg/ml;
Target
Alternative Names
CERS4; ceramide synthase 4; LAG1 homolog, ceramide synthase 4 , LAG1 longevity assurance homolog 4 (S. cerevisiae) , LASS4; FLJ12089; Trh1; LAG1 homolog, ceramide synthase 4; LAG1 longevity assurance homolog 4; LASS4;
Product Background
Antigen Description
May be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing different fatty acid donors (N-linked stearoyl- (C18) or arachidoyl- (C20) ceramides) in a fumonisin B1-independent manner.
Pathway
Ceramide biosynthesis, organism-specific biosystem; Ceramide biosynthesis, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid de novo biosynthesis, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem.
Citations
Publication ()
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COA
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