Recombinant full length protein corresponding to Human CENPP aa 1-288.Sequence: MDAELAEVRALQAEIAALRRACEDPPAPWEEKSRVQKSFQAIHQFNLEGW KSSKDLKNQLGHLESELSFLSTLTGINIRNHSKQTEDLTSTEMTEKSIRK VLQRHRLSGNCHMVTFQLEFQILEIQNKERLSSAVTDLNIIMEPTECSEL SEFVSRAEERKDLFMFFRSLHF
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex.
Pathway
Cell Cycle; Cell Cycle, Mitotic; Chromosome Maintenance; DNA Replication; Deposition of New CENPA-containing Nucleosomes at the Centromere; M Phase; Mitotic M-M/G1 phases
Citations
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