Rabbit Anti-Human CDKN2D (a.a. 65-166) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

KLH conjugated synthetic peptide derived from human CDKN2D/p19 INK4d: 65-166/166

Conjugate

Application Notes

ELISA: 1:5000-10000

General Notes

This product (Catalog No. DPABH-03401) is a rabbit-derived IgG polyclonal antibody raised against human CDKN2D, targeting the amino acid region 65–166 of the protein. This antibody exhibits cross-reactivity with CDKN2D from mouse and rat. It has been affinity purified by Protein A. The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported.
DPABH-03401 is suitable for use in ELISA (1:5,000–1:10,000) application.
DPABH-03401 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

CDK inhibitor p19INK4d; CDKN2D; cell cycle inhibitor, Nur77 associating protein; Cyclin dependent kinase inhibitor 2D; Cyclin-dependent kinase 4 inhibitor D; Cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4); inhibitor of cyclin-dependent kinase 4d; INK4D; p19; p19-INK4D; p19INK4d; Similar to cyclin-dependent kinase inhibitor 2D; CDN2D_HUMAN

Entrez Gene ID

UniProt ID