Anti-CDK6 monoclonal antibody (DCABH-1628) Knockout Validated

Rabbit anti-Human CDK6 monoclonal antibody for WB, IHC-P, ICC, FC

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS5626
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to residues in C-terminus of Human Cdk6.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/50000 - 1/200000; IHC-P: 1/100 - 1/250; ICC: 1/100 - 1/250; Flow Cyt: 1/100 - 1/1000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CDK6; cyclin-dependent kinase 6; PLSTIRE; cell division protein kinase 6; serine/threonine-protein kinase PLSTIRE; MGC59692
Entrez Gene ID
UniProt ID

Product Background


Pathway
B Cell Receptor Signaling Pathway, organism-specific biosystem; C-MYB transcription factor network, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, organism-specific biosystem; Cell cycle, conserved biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Boussiotis, VA; Chen, ZM; et al. Altered T-cell receptor+CD28-mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease. BLOOD 97:565-571(2001).
Kiyota, A; Shintani, S; et al. Anti-epidermal growth factor receptor monoclonal antibody 225 upregulates p27(KIP1) and p15(INK4B) and induces G1 arrest in oral squamous carcinoma cell lines. ONCOLOGY 63:92-98(2002).

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