Anti-CDK5RAP2 monoclonal antibody, clone 638DU33.0.3

Antibody Isotype

IgM

Clone

638DU33.0.3

Species Reactivity

Human

Conjugate

Application Notes

WB: 1:500-2000

Alternative Names

CDK5RAP2; CEP215; KIAA1633; CDK5 regulatory subunit-associated protein 2; CDK5 activator-binding protein C48; Centrosome-associated protein 215

Entrez Gene ID

UniProt ID

Antigen Description

Neuronal CDC2-like kinase, which is involved in the regulation of neuronal differentiation, is composed of a catalytic subunit, CDK5, and an activating subunit, p25NCK5A. The protein encoded by this gene binds to p25NCK5A and therefore may be involved in neuronal differentiation. The encoded protein may also be a substrate of neuronal CDC2-like kinase. Multiple transcript variants exist for this gene, but the full-length nature of only two has been determined.

Pathway

Cell Cycle; Cell Cycle, Mitotic; Centrosome maturation; G2/M Transition; Loss of Nlp from mitotic centrosomes; Loss of proteins required for interphase microtubule organization??from the centrosome; Mitotic G2-G2/M phases; Recruitment of mitotic centrosome proteins and complexes;