This product (Catalog No. DPABH-04499) is a rabbit-derived polyclonal antibody raised against human CDK18. It has been affinity purified by Protein A. CDK18 (Cyclin-dependent kinase 18), also known as PCTAIRE3 or PCTK3, is a serine/threonine protein kinase belonging to the CDK family that plays crucial roles in regulating the cell cycle, DNA repair, and neuronal differentiation. It is highly expressed in the brain, where it influences oligodendrocyte precursor cell differentiation and tau phosphorylation. CDK18 is also involved in promoting homologous recombination (HR) and resistance to PARP inhibitors in cancers like glioblastoma. DPABH-04499 is suitable for use in IF (immunofluorescence) (1:20–1:100) application. DPABH-04499 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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