Anti-CDC27 monoclonal antibody (DCABH-49)
Mouse anti-Human CDC27 monoclonal antibody for IP, WB, IHC-Fr, IHC-P, ELISA, FC
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Mouse, Rat, Cow, Dog, Human, Xenopus laevis
Synthetic peptide conjugated to KLH, corresponding to amino acids 814-823 of Human Cdc27.
WB: 1 - 2 μg/ml; Flow Cyt: 1μg/106 cells;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
CDC27; cell division cycle 27 homolog (S. cerevisiae); cell division cycle 27 , D17S978E, D0S1430E; cell division cycle protein 27 homolog; ANAPC3; anaphase promoting complex subunit 3
APC/C complex, organism-specific biosystem; APC/C complex, conserved biosystem; APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem;
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Kallio, M; Weinstein, J; et al. Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events. JOURNAL OF CELL BIOLOGY 141:1393-1406(1998).
Shikata, K; Ohta, S; et al. The human homologue of fission yeast cdc27, p66, is a component of active human DNA polymerase delta. JOURNAL OF BIOCHEMISTRY 129:699-708(2001).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.