Anti-CDC20 monoclonal antibody, clone BS23

Antibody Isotype

IgG1

Clone

BS23

Species Reactivity

Human

Immunogen

Urea-denatured recombinant His6 fusion protein corresponding to human CDC20.

Conjugate

Application Notes

Flow Cytometry (0.5-1 ug/million cells);
Immunofluorescence (0.5-1 μg/mL);
Immunohistochemistry (0.5-1 μg/mL for 30 min at RT);
Immunoprecipitation (0.5-1 ug/500 ug protein lysate);
WB (0.5-1 μg/mL)

Alternative Names

CDC20; cell division cycle 20 homolog (S. cerevisiae); CDC20 (cell division cycle 20, S. cerevisiae, homolog) , CDC20 cell division cycle 20 homolog (S. cerevisiae); cell division cycle protein 20 homolog; CDC20A; p55CDC; CDC20 cell division cycle 20 homo

Entrez Gene ID

UniProt ID

Antigen Description

CDC20 appears to act as a regulatory protein interacting with several other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes, nuclear movement prior to anaphase and chromosome separation.

Pathway

APC/C complex, organism-specific biosystem; APC/C complex, conserved biosystem; APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Cyclin B, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, or