CDA (Cytidine deaminase) scavengers exogenous and endogenous cytidine and 2-deoxycytidine for UMP synthesis. Growth inhibition of granulocyte-macrophage colony foring cells by human cytidine deaminase requires the catalytic function of the protein. It is highly expressed in granulocytes.
Pathway
Drug metabolism - other enzymes; Fluoropyrimidine Activity; Metabolic pathways; Metabolism; Metabolism of nucleotides; Pyrimidine metabolism;
Citations
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