General Notes
This product (Catalog No. DPABH-09268) is a rabbit-derived polyclonal antibody raised against human CD320, targeting the amino acid region 36–229 of the protein. It has been affinity purified by Protein A. CD320, also known as 8D6, 8D6A or TCblR, is a single-pass type I membrane protein containing 2 LDL-receptor class A domains. Expressed abundantly on follicular dendritic cells (FDCs), CD320 has been shown to enhance proliferation of germinal center (GC) B cells. It is the receptor for cellular uptake of transcobalamin-bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC). CD320 has a calculated molecular mass of 29 kDa.
DPABH-09268 is suitable for use in Western blot (WB) (1:500–1:3,000), IHC (1:200–1:800), IF/ICC (1:200–1:800) applications.
DPABH-09268 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.