Mouse myeloma cell line NS0-derived recombinant human 2B4/CD244/SLAMF4. Cys22-Arg221 Accession Number NP_057466
Conjugate
Unconjugated
Applications
Application Notes
Western Blot 0.1 μg/mL; Flow Cytometry 2.5 μg/106 cells; Immunohistochemistry 5-15 μg/mL; ELISA Capture 0.2-0.8 μg/mL; ELISA Detection 0.1-0.4 μg/mL We recommend the following for sandwich ELISA (Capture - Detection): DPABY-319 - DPABY-516
Target
Alternative Names
CD244; CD244 molecule, natural killer cell receptor 2B4; 2B4; NAIL; Nmrk; NKR2B4; SLAMF4; natural killer cell receptor 2B4; h2B4; SLAM family member 4; NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; NK cell activation inducing li
2B4, also known as CD244, is a cell surface glycoprotein belonging to the CD2 subgroup of the immunoglobulin superfamily. It acts as a high-affinity receptor for CD48. It is expressed by natural killer (NK) cells and CD8+ T cell subsets. It can regulate killing by CD8+ T cells and NK cells, and IFN-gamma secretion by NK cells. It may also regulate NK cell and T cell proliferation.
Pathway
Cell surface interactions at the vascular wall; Hemostasis; Natural killer cell mediated cytotoxicity;
Citations
Publication ()
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COA
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