Anti-CCT3 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human CCT3 is used for rabbit immunization.

Conjugate

Alternative Names

CCT3; chaperonin containing TCP1, subunit 3 (gamma); TRIC5; T-complex protein 1 subunit gamma; Cctg; hTRiC5; T-complex protein 1, gamma subunit; TCP1 (t-complex-1) ring complex, polypeptide 5; CCTG; PIG48; CCT-gamma; TCP-1-gamma;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Pathway

Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Cooperation of Prefoldin and TriC/CCTin actin and tubulin folding, organism-specific biosystem; Folding of actin by CCT/TriC, organism-specific biosystem; Formation of tubulin folding intermediates by CCT/TriC, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Prefoldin mediated transfer of substrateto CCT