Anti-CCL22 polyclonal antibody [Biotin]

Antibody Isotype

IgG

Species Reactivity

Mouse

Immunogen

E. coli-derived recombinant mouse CCL22/MDC . Gly25-Ser92 Accession Number Q9QZU2

Conjugate

Application Notes

Western Blot: 0.1 μg/mL; ELISA Capture: 2-8 μg/mL; ELISA Detection: 0.1-0.4 μg/mL
We recommend the following for sandwich ELISA (Capture - Detection):
DCABY-4008 - DPABY-591

Alternative Names

CCL22; chemokine (C-C motif) ligand 22; MDC; DCBCK; ABCD-1; Scya22; C-C motif chemokine 22; CC chemokine ABCD-1; small-inducible cytokine A22; activated B and dendritic cell-derived; small inducible cytokine subfamily A22; dendritic cell and B cell derive

Entrez Gene ID

UniProt ID

Antigen Description

Macrophage-derived chemokine (MDC), also named stimulated T cell chemotactic protein (STCP-1) and ABCD-1, and now designated as CCL22, is a CC chemokine initially isolated from clones of monocyte-derived macrophages. At the amino acid sequence level, MDC shows less than 35% identity to other CC chemokine family members. Human MDC is expressed in dendritic cells, macrophages and activated monocytes. In addition, MDC expression is detected in thymus, lymph node and appendix tissues. At the amino acid sequence level, mouse and human MDC share 64% identity and 83% similarity.

Pathway

Chemokine receptors bind chemokines; Chemokine signaling pathway; Class A/1 (Rhodopsin-like receptors); Cytokine-cytokine receptor interaction; GPCR ligand binding; Peptide ligand-binding receptors; Signal Transduction; Signaling by GPCR;