Coiled-coil domain-containing protein 53 is a protein that in humans is encoded by the CCDC53 gene. CCDC53 (coiled-coil domain containing 53) is a protein-coding gene. Diseases associated with CCDC53 include paraplegia, and spasticity. GO annotations related to this gene include protein binding. Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting.
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