General Notes
This product (Catalog No. DPABH-03445) is a rabbit-derived polyclonal antibody raised against human CCDC105, targeting the amino acid region 151–499 of the protein. It has been affinity purified by Protein A. CCDC105 (Coiled-Coil Domain Containing 105) is a protein-coding gene that encodes a coiled-coil domain–rich protein, typically associated with structural and regulatory roles in cells. Although its precise biochemical function is not fully defined, proteins with coiled-coil domains commonly mediate protein–protein interactions and contribute to the assembly of macromolecular complexes. CCDC105 has been implicated in cytoskeletal organization, particularly in microtubule- or centrosome-related processes, suggesting a potential role in cell division, intracellular transport, or structural maintenance. Expression analyses indicate tissue-specific or developmentally regulated patterns, and some studies have suggested involvement in spermatogenesis or ciliary/flagellar function, consistent with other coiled-coil proteins enriched in motile structures.
DPABH-03445 is suitable for use in Western blot (WB) (1:500–1:2,000), IHC (1:20–1:200), IF-P (1:50–1:500) applications.
DPABH-03445 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
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