CBLL1 (NP_079090, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. The sequence is MDHTDNELQGTNSSGSLGGLDVRRRIPIKLISKQANKAKPAPRTQRTINRMPAKAPPGDE EGFDYNEEERYDCKGGELFANQRRFPGHLFWDFQINILGE
Conjugate
Unconjugated
Target
Alternative Names
CBLL1; Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase; HAKAI; RNF188; E3 ubiquitin-protein ligase Hakai; c-Cbl-like protein 1; RING finger protein 188; E-cadherin binding protein E7; Cbl proto-oncogene, E3 ubiquitin protein ligase-like 1; casitas
This gene encodes an E3 ubiquitin-ligase for the E-cadherin complex and mediates its ubiquitination, endocytosis, and degradation in the lysosomes. The encoded protein contains a RING-finger domain and is also thought to have a role in control of cell proliferation. A related pseudogene has been identified on chromosome X. Alternative splicing results in a non-coding transcript variant.
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