Anti-CASZ1 polyclonal antibody (DPABH-22951)

Rabbit anti-Human CASZ1 (internal region) polyclonal antibody for WB Datasheet

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Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide corresponding to an internal region of Human CASZ1.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000 - 1/5000.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
CASZ1; castor zinc finger 1; CST; SRG; CAS11; ZNF693
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CASZ1 (Castor Zinc Finger 1) is a Protein Coding gene. Diseases associated with CASZ1 include retroperitoneal sarcoma and chromosome 1p36 deletion syndrome. The protein encoded by this gene is a zinc finger transcription factor. The encoded protein may function as a tumor suppressor, and single nucleotide polymorphisms in this gene are associated with blood pressure variation. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Antigen Description
Probable transcription factor. Transcription factor involved in vascular assembly and morphogenesis through direct transcriptional regulation of EGFL7. Putative survival-related protein is a protein that in humans is encoded by the CASZ1 gene. 0The function about CASZ1 antigen include DNA binding; metal ion binding.

Citations


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References


Beckervordersandforth, RM; Rickert, C; et al. Subtypes of glial cells in the Drosophila embryonic ventral nerve cord as related to lineage and gene expression. MECHANISMS OF DEVELOPMENT 125:542-557(2008).
Kambadur, R; Koizumi, K; et al. Regulation of POU genes by castor and hunchback establishes layered compartments in the Drosophila CNS. GENES & DEVELOPMENT 12:246-260(1998).

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