Anti-CAPN11 monoclonal antibody (DCABH-10828) Made to order

Rabbit anti-Human CAPN11 monoclonal antibody for WB, ELISA

View other CAPN11 antibodies

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
A synthetic peptide of human CAPN11 is used for rabbit immunization.
Conjugate
Unconjugated

Target


Alternative Names
CAPN11; calpain 11; calpain-11; CANP 11; calcium-activated neutral proteinase 11; calpain11
Entrez Gene ID
UniProt ID

Product Background


Gene summary
CAPN11 (Calpain 11) is a Protein Coding gene. Among its related pathways are Degradation of the extracellular matrix and Integrin Pathway. GO annotations related to this gene include calcium ion binding and calcium-dependent cysteine-type endopeptidase activity. An important paralog of this gene is CAPN9. Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis.
Antigen Description
Calpains constitute a family of intracellular calcium-dependent cysteine proteases. There are eight members in this superfamily. They consist of a variable 80 kDa subunit and an invariant 30 kDa subunit. This calpain protein appears to have protease activity and calcium-binding ability. A similar mouse protein may play a functional role in spermatogenesis and in the regulation of calcium-dependent signal transduction events during meiosis. Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. The function about CAPN11 antigen include calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; peptidase activity.
Pathway
Integrin-mediated cell adhesion, organism-specific biosystem.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


NEUMAR, RW; DEGRACIA, DJ; et al. EUKARYOTIC INITIATION-FACTOR 4E DEGRADATION DURING BRAIN ISCHEMIA. JOURNAL OF NEUROCHEMISTRY 65:1391-1394(1995).
Baba, T; Yamaguchi, M; et al. Stimulatory effect of regucalcin on proteolytic activity is impaired in the kidney cortex cytosol of rats with saline ingestion. MOLECULAR AND CELLULAR BIOCHEMISTRY 206:1-6(2000).

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