Anti-CACYBP monoclonal antibody, clone 8E22

Clone

8E22

Species Reactivity

Human

Immunogen

Recombinant protein corresponding to human CACYBP.

Conjugate

Application Notes

WB (1:500-1:2000); Immunofluorescence (1:200-1:1000); ELISA (1:10000) & The optimal working dilution should be determined by the end user.

Alternative Names

CACYBP; calcyclin binding protein; calcyclin-binding protein; S100A6BP; SIP; hCacyBP; S100A6-binding protein; Siah-interacting protein (SIP); growth-inhibiting gene 5 protein; GIG5; PNAS-107; RP1-102G20.6; MGC87971;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Pathway

Wnt signaling pathway, organism-specific biosystem; Wnt signaling pathway, conserved biosystem;