Anti-CACNB3 monoclonal antibody, clone 8E2

Antibody Isotype

IgG1

Clone

8E2

Species Reactivity

Mouse

Immunogen

Synthetic peptide corresponding to Mouse CACNB3. beta3 subunit of high-coltage-gated calcium channels-GST fusion proteinDatabase link: P54285

Conjugate

Alternative Names

CACNB3; calcium channel, voltage-dependent, beta 3 subunit; voltage-dependent L-type calcium channel subunit beta-3; CAB3; Ca(v)beta3; calcium channel beta 3 subunit; calcium channel voltage-dependent subunit beta 3; Beta3; Cchb3;

Entrez Gene ID

UniProt ID

Antigen Description

The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.

Pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem;