Synthetic peptide corresponding to a region within N-terminal amino acids 108-157 (TPQSSGDPSS RRPLCRPAPR EEGARGSQRV LPQAHCRPRE ALPAAASRPS) of Human CABP (NP_001028849).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml.
Target
Alternative Names
CABP1; calcium binding protein 1; CALBRAIN; HCALB_BR; calcium-binding protein 1; caldendrin; calcium binding protein 5;
Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration.
Citations
Publication ()
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