A synthetic peptide of human C7orf27 is used for rabbit immunization.
Conjugate
Unconjugated
Target
Alternative Names
BRAT1; BRCA1-associated ATM activator 1; BAAT1; RMFSL; C7orf27; HEAT repeat-containing protein C7orf27; BRCA1-associated protein required for ATM activation protein 1;
The protein encoded by this ubiquitously expressed gene interacts with the tumor suppressing BRCA1 (breast cancer 1) protein and and the ATM (ataxia telangiectasia mutated) protein. ATM is thought to be a master controller of cell cycle checkpoint signalling pathways that are required for cellular responses to DNA damage such as double-strand breaks that are induced by ionizing radiation and complexes with BRCA1 in the multi-protein complex BASC (BRAC1-associated genome surveillance complex). The protein encoded by this gene is thought to play a role in the DNA damage pathway regulated by BRCA1 and ATM.
Citations
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