Specifications
Species Reactivity
Rat, Human, Syrian Hamster
Immunogen
Recombinant full length mature protein, corresponding to amino acids 74-282 of Human GC1q R.
Applications
Application Notes
WB: 1/50; Flow Cyt: 1/50;
Target
Alternative Names
C1QBP; complement component 1, q subcomponent binding protein; HABP1; complement component 1 Q subcomponent-binding protein, mitochondrial; C1q globular domain binding protein; gC1Q R; gC1qR; hyaluronan binding protein 1; p32; SF2p32; splicing factor SF2
Product Background
Antigen Description
Binds to the globular "heads" of C1Q thus inhibiting C1 activation.
Pathway
Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Hemostasis, organism-specific biosystem; Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; Intrinsic Pathway, organism-specific biosystem;
Citations
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vandenBerg, RH; FaberKrol, MC; et al. Inhibition of the hemolytic activity of the first component of complement C1 by an Escherichia coli C1q binding protein. JOURNAL OF IMMUNOLOGY 156:4466-4473(1996).
Tahtouh, M; Garcon-Bocquet, A; et al. Interaction of HmC1q with leech microglial cells: involvement of C1qBP-related molecule in the induction of cell chemotaxis. JOURNAL OF NEUROINFLAMMATION 9:-(2012).
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Certificate of Analysis
