Anti-BRAF monoclonal antibody (DCABH-545)

Mouse anti-Human BRAF monoclonal antibody for WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
5C3
Species Reactivity
Human, Monkey
Immunogen
Protein expressed in 293T cells, transfected with Human B Raf expression vector (NM_004333).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
BRAF; v-raf murine sarcoma viral oncogene homolog B1; serine/threonine-protein kinase B-raf; BRAF1; p94; 94 kDa B-raf protein
Entrez Gene ID
UniProt ID

Product Background


Pathway
ARMS-mediated activation, organism-specific biosystem; Activation of NMDA receptor upon glutamate binding and postsynaptic events, organism-specific biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem;

Citations


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References


Grabellus, F; Worm, K; et al. The BRAF V600E Mutation in Papillary Thyroid Carcinoma Is Associated with Glucose Transporter 1 Overexpression. THYROID 22:377-382(2012).
Schirripa, M; Cremolini, C; et al. Role of NRAS mutations as prognostic and predictive markers in metastatic colorectal cancer. INTERNATIONAL JOURNAL OF CANCER 136:83-90(2015).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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Order Info: Anti-BRAF monoclonal antibody

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