Mouse anti-Human BMP8B polyclonal antibody

Species Reactivity

Human

Immunogen

BMP8B (NP_001711, 274 a.a. ~ 362 a.a) partial recombinant protein with GST tag. The sequence is KKSNELPQANRLPGIFDDVHGSHGRQVCRRHELYVSFQDLGWLDWVIAPQGYSAYYCEGE CSFPLDSCMNATNHAILQSLVHLMMPDAV

Conjugate

Alternative Names

BMP8B; bone morphogenetic protein 8b; OP2; BMP8; bone morphogenetic protein 8B; BMP-8; BMP-8B; osteogenic protein 2; bone morphogenetic protein 8 (osteogenic protein 2); dJ118J21.1 (bone morphogenetic protein 8 (osteogenic protein 2));

Entrez Gene ID

UniProt ID

Antigen Description

The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.

Pathway

Hippo signaling pathway; TGF-beta signaling pathway;