More than a black and white issue: ethnic identity, social dominance orientation, and support for the black lives matter movement
SELF AND IDENTITY
Authors: Holt, Lanier Frush; Sweitzer, Matthew D.
Abstract
The Black Lives Matter (BLM) Movement is the civil rights issue of our time, with opinions being fractured along racial lines. We examine how the relationship between identity constructs and BLM support operates differently among African Americans and White Americans. Our findings show ethnic identity predicts African Americans' attitudes on BLM, but is a poor predictor of White Americans' beliefs. Conversely, social dominance orientation better predicts White Americans' opinions of BLM, but does not associate with BLM attitudes among African Americans. The interaction of these constructs among White American respondents suggests that as White Americans discuss racial issues, the impact of social dominance is negated - leading to positive evaluations of BLM. These processes have implications for communication about racial issues.
Integrated miRNAome and mRNAome analysis identifies candidate genes that mediate testis development promoted by vitamin E in sheep
ANIMAL SCIENCE PAPERS AND REPORTS
Authors: Gao, Yuefeng; Lu, Wei; Qu, Yanghua; Jian, Luyang; Diao, Zhicheng; Xiu, Peng; Machaty, Zoltan; Luo, Hailing
Abstract
Vitamin E is known to improve testis development, yet the underlying mechanism responsible for this process remains poorly understood. To elucidate the mechanism, through which vitamin E facilitates testiscular development, we hypothesised that vitamin E improves testis development by promoting testis cell proliferation, while miRNAs also play a crucial role in the process. In order to test this hypothesis, we isolated primary testis cells from prepubertal sheep. Using the CCK-8 (Cell Counting Kit-8) assay we found that 800 mu M vitamin E supplementation enhanced cell proliferation. This was verified through western blot analysis of Ki67 and PCNA(proliferating cell nuclear antigen). Subsequently, cell cycle distribution induced by vitamin E was determined in the cells. Vitamin E markedly decreased the proportion of cells in the G1 phase and increased those in the S and G2/M phases in response to vitamin E supplementation. Meanwhile, vitamin E significantly increased expression of Cyclin B1 and Cyclin B3. Through the miRNAome and transcriptome technology, we identified a number of correlation pairs including miR-107-BLM (BLM RecQ like helicase), miR107-REL (REL proto-oncogene) and miR-493-3p-KLHL25 (kelch like family member 25), that are known to be involved in the regulation of correlation pairs participating in the cell cycle. Together these data demonstrate that 800 mu M vitamin E promotes testis cell proliferation and its action may be mediated by miR-107 and miR-493-3p that target the BLM, REL and KLHL25.