Apoptotic suppressor. The BIR motifs region interacts with TNF receptor associated factors 1 and 2 (TRAF1 and TRAF2) to form an heteromeric complex, which is then recruited to the tumor necrosis factor receptor 2 (TNFR2).
Pathway
Activated TLR4 signalling; Apoptosis; Apoptosis; Apoptotic cleavage of cellular proteins
Citations
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