BFSP1 (NP_001186, 567 a.a. ~ 664 a.a) partial recombinant protein with GST tag. The sequence is EESRRPCAMVTPGAEEPSIPEPPKPAADQDGAEVLGTRSRSLPEKGPPKALAYKTVEVVE SIEKISTESIQTYEETAVIVETMIGKTKSDKKKSGEKS
This gene encodes a lens-specific intermediate filament-like protein named filensin. The encoded protein is expressed in lens fiber cells after differentiation has begun. This protein functions as a component of the beaded filament which is a cytoskeletal structure found in lens fiber cells. Mutations in this gene are the cause of autosomal recessive cortical juvenile-onset cataract. Alternate splicing results in multiple transcript variants.
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