Anti-BECN1 monoclonal antibody (DCABH-725)

Mouse anti-Human BECN1 monoclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
5B21
Species Reactivity
Human
Immunogen
Recombinant full length protein of Human Beclin 1 (NP_003757) produced in HEK293T cells.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
BECN1; beclin 1, autophagy related; beclin 1 (coiled coil, moesin like BCL2 interacting protein); beclin-1; ATG6; ATG6 autophagy related 6 homolog (S. cerevisiae)
Entrez Gene ID
UniProt ID

Product Background


Pathway
Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; Senescence and Autophagy, organism-specific biosystem;

Citations


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References


Lozy, F; Cai-McRae, X; et al. ERBB2 overexpression suppresses stress-induced autophagy and renders ERBB2-induced mammary tumorigenesis independent of monoallelic Becn1 loss. AUTOPHAGY 10:662-676(2014).
Cooper, CDO; Lawrie, CH; et al. Identification and Characterization of Peripheral T-Cell Lymphoma-Associated SEREX Antigens. PLOS ONE 6:-(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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